¿Porque tengo problemas cuando autorizo vacaciones o alguna acción de vez en cuando?

Como puedo arreglar dicho inconveniente ya que algunas veces cuando ejecuto alguna acción que implica "guardar y procesar" y esta entidad posea una ruta de autorización me indica este error el elmah

   System.ServiceModel.FaultException
The execution of an InstancePersistenceCommand was interrupted because the instance key '4d19be4d-435a-0495-c6a4-c4ff7632d950' was not associated to an instance. This can occur because the instance or key has been cleaned up, or because the key is invalid. The key may be invalid if the message it was generated from was sent at the wrong time or contained incorrect correlation data.

System.ServiceModel.FaultException: The execution of an InstancePersistenceCommand was interrupted because the instance key '4d19be4d-435a-0495-c6a4-c4ff7632d950' was not associated to an instance. This can occur because the instance or key has been cleaned up, or because the key is invalid. The key may be invalid if the message it was generated from was sent at the wrong time or contained incorrect correlation data.

Server stack trace: 
   at System.ServiceModel.Channels.ServiceChannel.HandleReply(ProxyOperationRuntime operation, ProxyRpc& rpc)
   at System.ServiceModel.Channels.ServiceChannel.Call(String action, Boolean oneway, ProxyOperationRuntime operation, Object[] ins, Object[] outs, TimeSpan timeout)
   at System.ServiceModel.Channels.ServiceChannelProxy.InvokeService(IMethodCallMessage methodCall, ProxyOperationRuntime operation)
   at System.ServiceModel.Channels.ServiceChannelProxy.Invoke(IMessage message)

Exception rethrown at [0]: 
   at System.Runtime.Remoting.Proxies.RealProxy.HandleReturnMessage(IMessage reqMsg, IMessage retMsg)
   at System.Runtime.Remoting.Proxies.RealProxy.PrivateInvoke(MessageData& msgData, Int32 type)
   at Aseinfo.VH4.Infraestructura.Workflow.AuthorizationWorkflowService.IAuthorizationWorkflowService.AutorizarActividadEnFlujo(AutorizarActividadEnFlujoRequest request)
   at Aseinfo.VH4.General.Controllers.FlujosAutorizacionController.Autorizar(List`1 codigosActividades, String comentarios, String areaOrigen, String controllerOrigen, String actionOrigen) in c:\BuildAgent\work\5ed3bec7206feb61\VH4\General\Controllers\FlujosAutorizacionController.cs:line 418
   at lambda_method(Closure , ControllerBase , Object[] )
   at System.Web.Mvc.ReflectedActionDescriptor.Execute(ControllerContext controllerContext, IDictionary`2 parameters)
   at System.Web.Mvc.ControllerActionInvoker.InvokeActionMethod(ControllerContext controllerContext, ActionDescriptor actionDescriptor, IDictionary`2 parameters)
   at System.Web.Mvc.ControllerActionInvoker.<>c__DisplayClass15.<InvokeActionMethodWithFilters>b__12()
   at System.Web.Mvc.ControllerActionInvoker.InvokeActionMethodFilter(IActionFilter filter, ActionExecutingContext preContext, Func`1 continuation)
   at System.Web.Mvc.ControllerActionInvoker.InvokeActionMethodFilter(IActionFilter filter, ActionExecutingContext preContext, Func`1 continuation)
   at System.Web.Mvc.ControllerActionInvoker.InvokeActionMethodWithFilters(ControllerContext controllerContext, IList`1 filters, ActionDescriptor actionDescriptor, IDictionary`2 parameters)
   at System.Web.Mvc.ControllerActionInvoker.InvokeAction(ControllerContext controllerContext, String actionName)